Research Scientist - Protein Design and Optimization (Remote)

About the Role

We are seeking a dedicated, highly motivated Research Scientist - Protein Design and Optimization to join our team remotely. This role focuses on leading high-impact multidisciplinary research at the interface of protein design, ultra-high-throughput experimentation, and directed evolution. As a Research Scientist - Protein Design and Optimization, you will work on state-of-the-art approaches for antibody and protein design and optimization, collaborating with experts across various fields.

What You'll Do

• Develop high-throughput methods for screening protein-protein interactions to support the development of AI/ML predictive models.
• Guide the implementation and development of in vivo directed evolution capabilities.
• Oversee a team of automation engineers translating manual data generation workflows into custom automated environments.
• Serve as the primary point of contact between the AI/ML team and the experimental team, ensuring clarity and productive collaboration.
• Supervise and mentor technical staff, providing regular feedback on experimental design and data interpretation.
• Present research progress and results to internal leadership and funding sponsors.
• Lead the development of manuscripts, technical reports, and patent disclosures arising from the work.

Requirements

• Ph.D. in Biochemistry, Bioengineering, Synthetic Biology, Chemical Biology, Chemical Engineering, or a related field.
• Significant experience with yeast display and cell sorting (FACS, MACS).
• Advanced knowledge of protein-protein interaction biology, including antibody engineering principles.
• Experience with molecular cloning and DNA library construction.
• Advanced literacy in computational biology, with proficiency in Python or R.
• Experience supervising or mentoring junior researchers.
• Advanced communication skills to convey complex concepts clearly.

Nice to Have

• Experience with high-diversity libraries and multi-round selection campaigns.
• Experience with directed evolution approaches.
• Familiarity with automation environments and liquid handling platforms.

What We Offer

• Competitive salary range of $175,530 - $222,564 annually.
• Flexible Benefits Package including 401(k) and Relocation Assistance.
• Education Reimbursement Program.
• Flexible schedules depending on project needs.
• Opportunity to work in a dynamic, team-based environment.